Location: Irvine, CA
Employment Type: Full Time
Date Posted: 08/21/2021
Expire Date: 03/16/2022
Job Categories: Biotechnology and Pharmaceutical, Healthcare, Practitioner and Technician, Information Technology, Internet/E-Commerce, Science, Research & Development, Medical, Web Technology
AbbVie’s mission is to discover and deliver innovative medicines that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people’s lives across several key therapeutic areas: immunology, oncology, neuroscience, eye care, virology, women’s health and gastroenterology, in addition to products and services across its Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on Twitter, Facebook, Instagram, YouTube and LinkedIn.
The Clinical Pharmacology group, as part of Research, Nonclinical and Translational Sciences (RNTS) at AbbVie, is seeking a Senior Scientist – Modeling and Simulation. As a member of multidisciplinary teams, this individual will contribute both Pharmacokinetic and Modeling and Simulation (M&S) expertise to lead efforts to build in silico drug models that describe the relationship(s) between exposure (drug, antibody, biomarker) and response (pharmacodynamic, toxicodynamic) for both desired and undesired effects. These models will support early stage clinical development activities utilizing various sources of data from both nonclinical models and humans. This individual will have a strong background and expertise in pharmacokinetics and biopharmaceutics including IVIVC modeling, PBPK modeling, and exposure-response modeling in drug development. This individual should be comfortable with exploratory analyses and non-conventional modeling beyond systemic drug development including ophthalmology, neurotoxin, and aesthetics/dermatology. This scientist should be proactive, inquisitive, a self-starter who is eager to learn and thrives in a fast pace and independent environment, with a desire to interact as a modeling and simulation expert with matrix project teams.
Specific responsibilities include:
Education and Experience
Significant Work Activities
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Equal Employment Opportunity
At AbbVie, we value bringing together individuals from diverse backgrounds to develop new and innovative solutions for patients. As an equal opportunity employer we do not discriminate on the basis of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information gender identity or expression, sexual orientation, marital status, protected veteran status, or any other legally protected characteristic.